Quercetin ≥95% (HPLC), solid

Sinônimo(s):

3,3′,4′,5,6-Pentahydroxyflavone, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one

Empirical Formula (Hill Notation):

C₁₅H₁₀O₇

Número CAS:

117-39-5

Peso molecular:

302.24

Beilstein:

317313

Número EC:

204-187-1

ID de substância PubChem:

329823865

fonte biológica

synthetic (organic)

Nível de qualidade

100

teor

≥95% (HPLC)

forma

solid

pf

316.5 °C

solubilidade

water: practically insoluble

temperatura de armazenamento

room temp

SMILES string

OC1=CC(O)=C2C(OC(C3=CC=C(O)C(O)=C3)=C(O)C2=O)=C1

InChI

1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H

InChI key

REFJWTPEDVJJIY-UHFFFAOYSA-N

Aplicação

Quercetin has been used as an antioxidant which reversed the immunosuppressive effects of high glucose and hyperglycemic sera in type 2 diabetic patients.

It has been used as a detoxifying phytochemical in Apis mellifera.

It has been used as a positive control in DPPH (2,2- diphenyl-1-picryhydrazyl) radical scavenging assay. It has also been used for the preparation of calibration curve to determine total flavonoid content.

Embalagem

10, 100 g in glass bottle

Ações bioquímicas/fisiológicas

Quercetin is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. Quercetin may also inhibit fatty acid synthase activity.

Características e benefícios

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for ADME Tox and Kinase Phosphatase research. Discover more featured ADME Tox and Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.