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Esqualeno (Squalene) 98% - 500 Ml - Sigma

Código: 18685

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Sinônimo(s):

2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene

Fórmula linear:

[(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2

Número CAS:

111-02-4

Peso molecular:

410.72

Beilstein:

1728919

Número EC:

203-826-1

Número MDL:

MFCD00008912

ID de substância PubChem:

24899564

NACRES:

NA.25

Nível de qualidade

100

teor

≥98%

forma

liquid

cor

light yellow

índice de refração

n20/D 1.494 (lit.)

pb

285 °C/25 mmHg (lit.)

pf

−75 °C (lit.)

densidade

0.858 g/mL at 25 °C (lit.)

temperatura de armazenamento

2-8°C

SMILES string

CC(C)=CCCC(C)=CCCC(C)=CCC\C=C(/C)CCC=C(C)CCC=C(C)C

InChI

1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+

InChI key

YYGNTYWPHWGJRM-AAJYLUCBSA-N

Descrição geral

Squalene is a hydrocarbon containing double bond commonly found in shark liver oil. It is also present in vegetable oils but to a lesser extent.[1]

Aplicação

Squalene has been used:

  • as a standard for lipid identification and quantification[2]
  • in the isolation of macrophages for parasite incubation[3]
  • as a standard for the quantification of squalene in squalene analysis of oil samples[4]

 

Embalagem

10, 100, 500 mL in glass bottle

1 L in glass bottle

Ações bioquímicas/fisiológicas

Squalene is a biosynthetic precursor to all steroids. It acts as a cytoprotective agent to normal cells exposed to carcinogens and antitumor agents. Squalene helps in equalizing the blood cholesterol levels. It increases the production of HDL (high density lipoprotein) and the excretion of LDL (low density lipoprotein). This helps in reducing the risk of heart disease and protects the less stable body fats from oxidation. It is also used in treating hypercholesterolemia. Squalene is known to improve the efficiency of cholesterol lowering drugs. It also serves as an antioxidant by preventing the effects of free radical. It protects skin from drying and other environmental conditions such as oxidation, ultraviolet rays and pollutants. Squalene is known to promote wound healing.[5]

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