Potassium Antimonyl Tartrate Trihydrate 99% ACS reagent, ≥99%

Sinônimo(s):

Antimony potassium tartrate trihydrate, Tartar emetic

Empirical Formula (Hill Notation):

C₈H₄K₂O₁₂Sb₂ · 3H₂O

Número CAS:

28300-74-5

Peso molecular:

667.87

Número EC:

234-293-3

Número MDL:

MFCD00167056

ID de substância PubChem:

24863959

NACRES:

NA.21

grau

ACS reagent

Nível de qualidade

200

Ensaio

≥99%
99.0-103.0%

forma

powder

Impurezas

≤0.020 meq/g Titr. acid or base

perda

≤2.7% loss on drying

pf

≥300 °C (lit.)

solubilidade

water: soluble

traços de cátion

As: ≤0.015%

SMILES string

O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O

InChI

1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4

InChI key

WBTCZEPSIIFINA-UHFFFAOYSA-J

Descrição geral

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII).[1] Potassium antimonyl tartrate (PAT) is an antiparasitic agent[2] predominantly used for treating infections caused by the parasite Leishmania.[3] Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells.[4] Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.[5]

Aplicação

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.[6]

Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L).[7] It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.[8]