Sais Biliares (Bile Salts)

Sinônimo(s):

Bile acids sodium salt, cholic acid-deoxycholic acid sodium salt mixture, Bile acids sodium salt, Cholic acid-Deoxycholic acid sodium salt mixture

Número MDL:

MFCD00130648

NACRES:

NA.85

descrição

anionic

Nível de qualidade

200

esterilidade

non-sterile

Ensaio

40-60% (Cholic Acid ; approximately 50% sodium cholate and approximately 50% sodium deoxycholate, HPLC)

forma

powder

composição

cholic acid sodium salt, ~50%
deoxycholic acid sodium salt, ~50%

Impurezas

≤5% water

perda

≤5% loss on drying (water)

solubilidade

H₂O: 0.1 g/mL, clear, faintly yellow

application(s)

microbiology

temperatura de armazenamento

10-30°C

Descrição geral

Bile salt is an organic sodium salt with a conjugate of any of the bile acids along with either glycine or taurine. Biles salts are composed of four different kinds of bile acids - cholic, deoxycholic, chenodeoxycholic and lithocholic acids.
Bile salts are extracted under controlled conditions from purified fresh bile, to be used in bacteriological culture media, where it behaves as a selective inhibitory agent that enables isolation and identification of pathogens. For example, in MacConkey Agar/Broth.

Aplicação

Bile salts may be used as one of the selective agents to prevent the growth of injured Escherichia coli cells, in an experiment done in order to identify the specific agent in the selective media which would inhibit the growth of the injured Escherichia coli ML30 cells.[1] It may also be used for identification of isolates of Vibrio (Beneckea) vulnificus which is a halophilic bacterium, found responsible for causing several human infections.[2]

Ações bioquímicas/fisiológicas

Bile salts are surface-active steroid compounds and their primary physiological function is to aid in the digestion of lipophilic nutrients in intestinal tracts of vertebrates.[3]