Pyridostigmine bromide ≥98% (HPLC), Acetylcholinesterase inhibitor, solid

Sinônimo(s):

3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide

Sobre este item

Fórmula empírica (Notação de Hill):

C₉H₁₃BrN₂O₂

Número CAS:

101-26-8

Peso molecular:

261.12

Número CE:

202-929-9

Número MDL:

MFCD00079283

Código UNSPSC:

12352200

ID de substância PubChem:

24277865

NACRES:

NA.77

Nome do produto

Pyridostigmine bromide,

Ensaio

≥98% (HPLC)

Nível de qualidade

100

Formulário

solid

solubilidade

water: 100 mg/mL, clear to very slightly hazy, colorless

originador

Valeant

cadeia de caracteres SMILES

[Br-].CN(C)C(=O)Oc1ccc[n+](C)c1

InChI

1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1

chave InChI

VNYBTNPBYXSMOO-UHFFFAOYSA-M

Informações sobre genes

human ... ACHE(43)

Aplicação

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice,[1] in florimetric assay for acetylcholine secretion[2] and for measuring acetylcholine release from mice atrial tissue.[3]

Ações bioquímicas/fisiológicas

Acetylcholinesterase inhibitor.

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare.[4] Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract.[5] Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.[6]

Características e benefícios

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.