p-Toluenesulfonic acid monohydrate

ACS reagent grade, ≥98.5%, solid

Sinônimo(s):

4-Methylbenzenesulfonic acid monohydrate, 4-Toluenesulfonic acid monohydrate, PTSA monohydrate, TsOH monohydrate

Sobre este item

Fórmula linear:

CH₃C₆H₄SO₃H · H₂O

Número CAS:

6192-52-5

Peso molecular:

190.22

NACRES:

NA.21

PubChem Substance ID:

24865132

UNSPSC Code:

12352100

EC Number:

203-180-0

MDL number:

MFCD00142137

Beilstein/REAXYS Number:

3568023

Assay:

≥98.5%

Concentration:

≥98.5%

Form:

solid

Grade:

ACS reagent

Propriedades

Nome do produto

p-Toluenesulfonic acid monohydrate, ACS reagent, ≥98.5%

InChI key

KJIFKLIQANRMOU-UHFFFAOYSA-N

InChI

1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2

SMILES string

[H]O[H].Cc1ccc(cc1)S(O)(=O)=O

grade

ACS reagent

vapor density

5.9 (vs air)

assay

≥98.5%

form

solid

concentration

≥98.5%

clarity of soln

passes test

impurities

9.5-11.5% water

ign. residue

≤0.1%

mp

103-106 °C (lit.)

solubility

H₂O: 10g + 50 mL, clear, colorless

anion traces

sulfate (SO₄^2-): ≤0.3%

cation traces

Fe: ≤0.01%, Na: ≤0.002%, heavy metals (as Pb): ≤0.001%

functional group

tosylate

Quality Level

300

General description

p-Toluenesulfonic acid monohydrate, an oxonium salt[1], is an inexpensive and easy to handle organic catalyst used in organic synthesis.[2] The study of its crystalline structure shows that it is monoclinic with P2₁/c space group.[1] Its solubility in aqueous sulfuric acid solutions has been studied.[3]

Application

p-Toluenesulfonic acid monohydrate (p-TsOH·H₂O) may be used as a catalyst in the synthesis of the following:

• Unsymmetrical benzils.[4]
• Highly substituted piperidines.[2]
• 1,3,5-Trisubstituted benzenes by trimerization of alkynes.[5]
• Triazoloquinazolinone and benzimidazoquinazolinone derivatives.[6]
• 1,3,5-Trisubstituted pyrazoles derivatives.[7]
• Selenated ketene dithioacetals.[8]