Phloxine B

Powder

Sinônimo(s):

2′,4′,5′,7′-Tetrabromo-4,5,6,7-tetrachlorofluorescein disodium salt, Acid Red 92, Cyanosine, D&C;Red No. 28, Eosin 10B

Sobre este item

Fórmula empírica (Notação de Hill):

C₂₀H₂Br₄Cl₄Na₂O₅

Número CAS:

18472-87-2

Peso molecular:

829.63

UNSPSC Code:

12171500

NACRES:

NA.47

PubChem Substance ID:

24898359

EC Number:

242-355-6

MDL number:

MFCD00070627

Beilstein/REAXYS Number:

3887100

Nome do produto

Phloxine B, antibacterial fluorescent dye

InChI

1S/C20H4Br4Cl4O5.2Na/c21-5-1-3-17(9(23)15(5)29)32-18-4(2-6(22)16(30)10(18)24)20(3)8-7(19(31)33-20)11(25)13(27)14(28)12(8)26;;/h1-2,29-30H;;/q;2*+1/p-2

InChI key

OOYIOIOOWUGAHD-UHFFFAOYSA-L

SMILES string

[Na+].[Na+].[O-]c1c(Br)cc2c(Oc3c(Br)c([O-])c(Br)cc3C24OC(=O)c5c(Cl)c(Cl)c(Cl)c(Cl)c45)c1Br

form

powder

technique(s)

microbe id | staining: suitable

color

dark red

solubility

water: 1 mg/mL, clear, red

ε_max

1150-1300 at 546-550 nm in 50% ethanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

Application

Phloxine B has been used to trace the uptake of double stranded RNA by green peach aphids.[1] It has also been used to stain yeast strains.[2]

Biochem/physiol Actions

Phloxine B has been demonstrated as an alternative to Gram staining.[3] It was found to inhibit the growth of methicillin-resistant Staphylococcus aureus. Phloxine B stimulated and inhibited the channel activity of wild-type cystic fibrosis transmembrane conductance regulator (CFTR).[4] It has antibacterial properties. Phloxine B staining can be used to distinguish between gram-positive and gram-negative bacteria.[3]